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PRIMMO study protocol: a phase II study combining PD-1 blockade, radiation and immunomodulation to tackle cervical and uterine cancer

BACKGROUND: Immunotherapeutic approaches have revolutionized oncological practice but are less evaluated in gynecological malignancies. PD-1/PD-L1 blockade in gynecological cancers showed objective responses in 13–17% of patients. This could be due to immunosuppressive effects exerted by gynecologic...

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Detalles Bibliográficos
Autores principales: Tuyaerts, Sandra, Van Nuffel, An M. T., Naert, Eline, Van Dam, Peter A., Vuylsteke, Peter, De Caluwé, Alex, Aspeslagh, Sandrine, Dirix, Piet, Lippens, Lien, De Jaeghere, Emiel, Amant, Frédéric, Vandecasteele, Katrien, Denys, Hannelore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537207/
https://www.ncbi.nlm.nih.gov/pubmed/31138229
http://dx.doi.org/10.1186/s12885-019-5676-3