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The impact of At1r inhibition via losartan on the anti-leukaemic effects of doxorubicin in acute myeloid leukaemia

INTRODUCTION: Bone marrow renin–angiotensin system(RAS) modulates acute myeloid leukaemia(AML).The aim of this study is to clarify the relationships between RAS and AML, and to show the effect of losartan and doxorubicin treatment in AML cell lines. METHODS: AML cell lines including CESS, HL-60, MO-...

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Detalles Bibliográficos
Autores principales: Ghasemi, Mehdi, Okay, Mufide, Turk, Seyhan, Naeemaee, Ronak, Guver, Ebru, Malkan, Umit Y, Aksu, Salih, Sayinalp, Nilgun, Haznedaroglu, Ibrahim C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537254/
https://www.ncbi.nlm.nih.gov/pubmed/31117912
http://dx.doi.org/10.1177/1470320319851310