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CRKL regulates alternative splicing of cancer-related genes in cervical cancer samples and HeLa cell

BACKGROUND: Aberrant spliced isoforms are specifically associated with cancer progression and metastasis. The cytoplasmic adaptor CRKL (v-crk avian sarcoma virus CT10 oncogene homolog-like) is a CRK like proto-oncogene, which encodes a SH2 and SH3 (src homology) domain-containing adaptor protein. CR...

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Detalles Bibliográficos
Autores principales: Song, Qingling, Yi, Fengtao, Zhang, Yuhong, Jun Li, Daniel K., Wei, Yaxun, Yu, Han, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537309/
https://www.ncbi.nlm.nih.gov/pubmed/31133010
http://dx.doi.org/10.1186/s12885-019-5671-8