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CDKN2A copy number and p16 expression in malignant pleural mesothelioma in relation to asbestos exposure

BACKGROUND: Deletion of the CDKN2A locus is centrally involved in the development of several malignancies. In malignant pleural mesothelioma (MPM), it is one of the most frequently reported genomic alteration. MPM is strongly associated with a patients’ asbestos exposure. However, the status of CDKN...

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Detalles Bibliográficos
Autores principales: Kettunen, Eeva, Savukoski, Sauli, Salmenkivi, Kaisa, Böhling, Tom, Vanhala, Esa, Kuosma, Eeva, Anttila, Sisko, Wolff, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537412/
https://www.ncbi.nlm.nih.gov/pubmed/31138176
http://dx.doi.org/10.1186/s12885-019-5652-y