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The role of ubiquitin-specific peptidases in cancer progression

Protein ubiquitination is an important mechanism for regulating the activity and levels of proteins under physiological conditions. Loss of regulation by protein ubiquitination leads to various diseases, such as cancer. Two types of enzymes, namely, E1/E2/E3 ligases and deubiquitinases, are responsi...

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Detalles Bibliográficos
Autores principales: Young, Ming-Jer, Hsu, Kai-Cheng, Lin, Tony Eight, Chang, Wen-Chang, Hung, Jan-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537419/
https://www.ncbi.nlm.nih.gov/pubmed/31133011
http://dx.doi.org/10.1186/s12929-019-0522-0