Cargando…

The role of ubiquitin-specific peptidases in cancer progression

Protein ubiquitination is an important mechanism for regulating the activity and levels of proteins under physiological conditions. Loss of regulation by protein ubiquitination leads to various diseases, such as cancer. Two types of enzymes, namely, E1/E2/E3 ligases and deubiquitinases, are responsi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Young, Ming-Jer, Hsu, Kai-Cheng, Lin, Tony Eight, Chang, Wen-Chang, Hung, Jan-Jong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537419/ https://www.ncbi.nlm.nih.gov/pubmed/31133011 http://dx.doi.org/10.1186/s12929-019-0522-0

Ejemplares similares

Expression and Role of Ubiquitin-Specific Peptidases in Osteoblasts
por: Hariri, Hadla, et al.
Publicado: (2021)

Ubiquitin specific peptidases and prostate cancer
por: Guo, Yunfei, et al.
Publicado: (2023)

Role of Ubiquitin-Specific Peptidase 47 in Cancers and Other Diseases
por: Pan, Kailing, et al.
Publicado: (2021)

Ubiquitin‐specific peptidases: Players in bone metabolism
por: Shen, Jianlin, et al.
Publicado: (2023)

EGF-mediated inhibition of ubiquitin-specific peptidase 24 expression has a crucial role in tumorigenesis
por: Wang, S-A, et al.
Publicado: (2017)

Advances in the Development Ubiquitin-Specific Peptidase (USP) Inhibitors
por: Chen, Shiyao, et al.
Publicado: (2021)

Ubiquitin-specific peptidase 25 exacerbated osteoarthritis progression through facilitating TXNIP ubiquitination and NLRP3 inflammasome activation
por: Sui, Jie, et al.
Publicado: (2023)

Ubiquitin-specific peptidase 5 facilitates cancer stem cell-like properties in lung cancer by deubiquitinating β-catenin
por: Tung, Chia-Hao, et al.
Publicado: (2023)

Behavioral Characteristics of Ubiquitin-Specific Peptidase 46-Deficient Mice
por: Imai, Saki, et al.
Publicado: (2013)

Ubiquitin-specific peptidase 22 functions and its involvement in disease
por: Melo-Cardenas, Johanna, et al.
Publicado: (2016)

The Pleiotropic Ubiquitin-Specific Peptidase 16 and Its Many Substrates
por: Zheng, Jiahuan, et al.
Publicado: (2023)

Ubiquitin specific peptidase 37 and PCNA interaction promotes osteosarcoma pathogenesis by modulating replication fork progression
por: Chauhan, Ravi, et al.
Publicado: (2023)

Ubiquitin-Specific Peptidase 7: A Novel Deubiquitinase That Regulates Protein Homeostasis and Cancers
por: Zhou, Lin, et al.
Publicado: (2021)

Ubiquitin-specific peptidase 22 controls integrin-dependent cancer cell stemness and metastasis
por: Liu, Kun, et al.
Publicado: (2023)

Ubiquitin-specific peptidase 22 promotes proliferation and metastasis in human colon cancer
por: Yuan, Xiao, et al.
Publicado: (2019)

Ubiquitin-specific peptidase 37: an important cog in the oncogenic machinery of cancerous cells
por: Chauhan, Ravi, et al.
Publicado: (2021)

Ubiquitin specific peptidase 11 as a novel therapeutic target for cancer management
por: Liao, Yihao, et al.
Publicado: (2022)

Ubiquitin-specific peptidase 18 regulates the differentiation and function of Treg cells
por: Yang, Lu, et al.
Publicado: (2020)

Ring finger 220 promotes the stemness and progression of colon cancer cells via Ubiquitin specific peptidase 22-BMI1 axis
por: Yan, Jianwen, et al.
Publicado: (2021)

Ubiquitin Specific Peptidase 22 Regulates Histone H2B Mono-Ubiquitination and Exhibits Both Oncogenic and Tumor Suppressor Roles in Cancer
por: Jeusset, Lucile M-P., et al.
Publicado: (2017)

Transcriptome profiling data reveals ubiquitin-specific peptidase 9 knockdown effects
por: Glaab, Enrico, et al.
Publicado: (2019)

High expression of ubiquitin-specific peptidase 39 is associated with the development of vascular remodeling
por: He, Shuai, et al.
Publicado: (2017)

Ubiquitin-specific peptidase 14 maintains estrogen receptor α stability via its deubiquitination activity in endometrial cancer
por: Su, Yingjie, et al.
Publicado: (2022)

Knockdown of ubiquitin-specific peptidase 39 inhibited the growth of osteosarcoma cells and induced apoptosis in vitro
por: Gan, Zhihua, et al.
Publicado: (2017)

Ubiquitin specific peptidase 5 enhances STAT3 signaling and promotes migration and invasion in Pancreatic Cancer
por: Lian, Jie, et al.
Publicado: (2020)

Ubiquitin specific peptidase 5 promotes ovarian cancer cell proliferation through deubiquitinating HDAC2
por: Du, Yanhua, et al.
Publicado: (2019)

Anti-Inflammatory and Tau Phosphorylation–Inhibitory Effects of Eupatin
por: Chou, Ching-Hsuan, et al.
Publicado: (2020)

Ubiquitin-specific peptidase 10, a deubiquitinating enzyme: Assessing its role in tumor prognosis and immune response
por: Ye, Ziqi, et al.
Publicado: (2022)

miR-5000-3p confers oxaliplatin resistance by targeting ubiquitin-specific peptidase 49 in colorectal cancer
por: Zhuang, Yan-yan, et al.
Publicado: (2021)

EOAI, a ubiquitin-specific peptidase 5 inhibitor, prevents non-small cell lung cancer progression by inducing DNA damage
por: Zheng, Yuanyuan, et al.
Publicado: (2023)

Ubiquitin specific peptidase Usp53 regulates osteoblast versus adipocyte lineage commitment
por: Hariri, Hadla, et al.
Publicado: (2021)

Nm23-H1-stabilized hnRNPA2/B1 promotes internal ribosomal entry site (IRES)-mediated translation of Sp1 in the lung cancer progression
por: Hung, Chia-Yang, et al.
Publicado: (2017)

The deubiquitinating enzyme, ubiquitin‐specific peptidase 50, regulates inflammasome activation by targeting the ASC adaptor protein
por: Lee, Jae Young, et al.
Publicado: (2017)

Investigation of Anti-Tumor Effects of an MLK1 Inhibitor in Prostate and Pancreatic Cancers
por: Fan, Yu-Ching, et al.
Publicado: (2021)

Lysosomal peptidases—intriguing roles in cancer progression and neurodegeneration
por: Kos, Janko, et al.
Publicado: (2022)

Downregulation of ubiquitin-specific peptidase 39 suppresses the proliferation and induces the apoptosis of human colorectal cancer cells
por: Xing, Zhiyuan, et al.
Publicado: (2018)

Downregulation of ubiquitin-specific peptidase 39 suppresses the proliferation and induces the apoptosis of human colorectal cancer cells
por: Xing, Zhiyuan, et al.
Publicado: (2018)

Biological effects of ubiquitin-specific peptidase 22 on thyroid papillary cancer cells and its mechanism of action
por: Wang, Hong-Qun, et al.
Publicado: (2020)

Ubiquitin-Specific Peptidase 22, a Histone Deubiquitinating Enzyme, Is a Novel Poor Prognostic Factor for Salivary Adenoid Cystic Carcinoma
por: Dai, Wei, et al.
Publicado: (2014)

Ubiquitin-specific Peptidase 42 (USP42) Functions to Deubiquitylate Histones and Regulate Transcriptional Activity
por: Hock, Andreas K., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_0fq8emflcjnugq96v6ckp46pho