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Longitudinal study of leukocyte DNA methylation and biomarkers for cancer risk in older adults

BACKGROUND: Changes in DNA methylation over the course of life may provide an indicator of risk for cancer. We explored longitudinal changes in CpG methylation from blood leukocytes, and likelihood of future cancer diagnosis. METHODS: Peripheral blood samples were obtained at baseline and at follow-...

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Detalles Bibliográficos
Autores principales: Bartlett, Alexandra H., Liang, Jane W., Sandoval-Sierra, Jose Vladimir, Fowke, Jay H., Simonsick, Eleanor M., Johnson, Karen C., Mozhui, Khyobeni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537435/
https://www.ncbi.nlm.nih.gov/pubmed/31149338
http://dx.doi.org/10.1186/s40364-019-0161-3