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Acute Fingolimod Effects on Baroreflex and Cardiovascular Autonomic Control in Multiple Sclerosis

BACKGROUND: Fingolimod, an oral drug used in multiple sclerosis (MS) treatment, exerts its action through S1P-receptor engagement. These receptors are also expressed in heart and endothelial cells. The engagement of receptors on the atrial heart myocytes may cause a slowing effect on heart rate (HR)...

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Detalles Bibliográficos
Autores principales: Racca, Vittorio, Rovaris, Marco, Cavarretta, Rosella, Vaini, Emanuele, Toccafondi, Anastasia, Di Rienzo, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537493/
https://www.ncbi.nlm.nih.gov/pubmed/31205439
http://dx.doi.org/10.1177/1179573519849945