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Inflammation as a Cancer Co-Initiator: New Mechanistic Model Predicts Low/Negligible Risk at Noninflammatory Carcinogen Doses
Linear-no-threshold (LNT) risk extrapolation has long been applied to estimate risks posed by low-level environmental carcinogen exposures, based on the 60-year-old multistage somatic mutation/clonal expansion (MSM) cancer theory. Recent evidence supports an alternative theory: Malignant tumors aris...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE Publications
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537503/ https://www.ncbi.nlm.nih.gov/pubmed/31205456 http://dx.doi.org/10.1177/1559325819847834 |