The Roles of Intracellular Chaperone Proteins, Sigma Receptors, in Parkinson’s Disease (PD) and Major Depressive Disorder (MDD)

Sigma receptors, including Sigma-1 receptors and Sigma-2 receptors, are highly expressed in the CNS. They are intracellular chaperone proteins. Sigma-1 receptors localize mainly at the mitochondria-associated endoplasmic reticulum (ER) membrane (MAM). Upon stimulation, they translocate from MAM to p...

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Detalles Bibliográficos
Autores principales: Yang, Kai, Wang, Changcai, Sun, Taolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537631/
https://www.ncbi.nlm.nih.gov/pubmed/31178723
http://dx.doi.org/10.3389/fphar.2019.00528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537631/
https://www.ncbi.nlm.nih.gov/pubmed/31178723
http://dx.doi.org/10.3389/fphar.2019.00528

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