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Design, synthesis, molecular modelling, and biological evaluation of novel substituted pyrimidine derivatives as potential anticancer agents for hepatocellular carcinoma

New anticancer agents are highly needed to overcome cancer cell resistance. A novel series of pyrimidine pyrazoline-anthracene derivatives (PPADs) (4a-t) were designed and synthesised. The anti-liver cancer activity of all compounds was screened in vitro against two hepatocellular carcinoma (HCC) ce...

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Detalles Bibliográficos
Autores principales:	Ahmed, Naglaa Mohamed, Youns, Mahmoud, Soltan, Moustafa Khames, Said, Ahmed Mohammed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537702/ https://www.ncbi.nlm.nih.gov/pubmed/31117890 http://dx.doi.org/10.1080/14756366.2019.1612889

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