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HDAC1-mediated repression of the retinoic acid-responsive gene ripply3 promotes second heart field development

Coordinated transcriptional and epigenetic mechanisms that direct development of the later differentiating second heart field (SHF) progenitors remain largely unknown. Here, we show that a novel zebrafish histone deacetylase 1 (hdac1) mutant allele cardiac really gone (crg) has a deficit of ventricu...

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Detalles Bibliográficos
Autores principales: Song, Yuntao Charlie, Dohn, Tracy E., Rydeen, Ariel B., Nechiporuk, Alex V., Waxman, Joshua S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538190/
https://www.ncbi.nlm.nih.gov/pubmed/31091225
http://dx.doi.org/10.1371/journal.pgen.1008165