Cargando…

MicroRNA26 attenuates vascular smooth muscle maturation via endothelial BMP signalling

As small regulatory transcripts, microRNAs (miRs) act as genetic ‘fine tuners’ of posttranscriptional events, and as genetic switches to promote phenotypic switching. The miR miR26a targets the BMP signalling effector, smad1. We show that loss of miR26a leads to hemorrhage (a loss of vascular stabil...

Descripción completa

Detalles Bibliográficos
Autores principales: Watterston, Charlene, Zeng, Lei, Onabadejo, Abidemi, Childs, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538191/
https://www.ncbi.nlm.nih.gov/pubmed/31091229
http://dx.doi.org/10.1371/journal.pgen.1008163