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MicroRNA26 attenuates vascular smooth muscle maturation via endothelial BMP signalling
As small regulatory transcripts, microRNAs (miRs) act as genetic ‘fine tuners’ of posttranscriptional events, and as genetic switches to promote phenotypic switching. The miR miR26a targets the BMP signalling effector, smad1. We show that loss of miR26a leads to hemorrhage (a loss of vascular stabil...
Autores principales: | Watterston, Charlene, Zeng, Lei, Onabadejo, Abidemi, Childs, Sarah J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538191/ https://www.ncbi.nlm.nih.gov/pubmed/31091229 http://dx.doi.org/10.1371/journal.pgen.1008163 |
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