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Selection of Candida albicans trisomy during oropharyngeal infection results in a commensal-like phenotype

When the fungus Candida albicans proliferates in the oropharyngeal cavity during experimental oropharyngeal candidiasis (OPC), it undergoes large-scale genome changes at a much higher frequency than when it grows in vitro. Previously, we identified a specific whole chromosome amplification, trisomy...

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Detalles Bibliográficos
Autores principales: Forche, Anja, Solis, Norma V., Swidergall, Marc, Thomas, Robert, Guyer, Alison, Beach, Annette, Cromie, Gareth A., Le, Giang T., Lowell, Emily, Pavelka, Norman, Berman, Judith, Dudley, Aimeé M., Selmecki, Anna, Filler, Scott G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538192/
https://www.ncbi.nlm.nih.gov/pubmed/31091232
http://dx.doi.org/10.1371/journal.pgen.1008137