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BDNF Alleviates Neuroinflammation in the Hippocampus of Type 1 Diabetic Mice via Blocking the Aberrant HMGB1/RAGE/NF-κB Pathway

Diabetes is a systemic disease that can cause brain damage such as synaptic impairments in the hippocampus, which is partly because of neuroinflammation induced by hyperglycemia. Brain-derived neurotrophic factor (BDNF) is essential in modulating neuroplasticity. Its role in anti-inflammation in dia...

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Detalles Bibliográficos
Autores principales: Han, Rongrong, Liu, Zeyue, Sun, Nannan, Liu, Shu, Li, Lanlan, Shen, Yan, Xiu, Jianbo, Xu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538223/
https://www.ncbi.nlm.nih.gov/pubmed/31165005
http://dx.doi.org/10.14336/AD.2018.0707