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BDNF Alleviates Neuroinflammation in the Hippocampus of Type 1 Diabetic Mice via Blocking the Aberrant HMGB1/RAGE/NF-κB Pathway
Diabetes is a systemic disease that can cause brain damage such as synaptic impairments in the hippocampus, which is partly because of neuroinflammation induced by hyperglycemia. Brain-derived neurotrophic factor (BDNF) is essential in modulating neuroplasticity. Its role in anti-inflammation in dia...
Autores principales: | Han, Rongrong, Liu, Zeyue, Sun, Nannan, Liu, Shu, Li, Lanlan, Shen, Yan, Xiu, Jianbo, Xu, Qi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JKL International LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538223/ https://www.ncbi.nlm.nih.gov/pubmed/31165005 http://dx.doi.org/10.14336/AD.2018.0707 |
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