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Classical and intermediate monocytes scavenge non-transferrin-bound iron and damaged erythrocytes

Myelomonocytic cells are critically involved in iron turnover as aged RBC recyclers. Human monocytes are divided in 3 subpopulations of classical, intermediate, and nonclassical cells, differing in inflammatory and migratory phenotype. Their functions in iron homeostasis are, however, unclear. Here,...

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Detalles Bibliográficos
Autores principales: Haschka, David, Petzer, Verena, Kocher, Florian, Tschurtschenthaler, Christoph, Schaefer, Benedikt, Seifert, Markus, Sopper, Sieghart, Sonnweber, Thomas, Feistritzer, Clemens, Arvedson, Tara L., Zoller, Heinz, Stauder, Reinhard, Theurl, Igor, Weiss, Guenter, Tymoszuk, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538345/
https://www.ncbi.nlm.nih.gov/pubmed/30996139
http://dx.doi.org/10.1172/jci.insight.98867