Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDA) is a heterogeneous disease comprised of a basal-like subtype with mesenchymal gene signatures, undifferentiated histopathology and worse prognosis compared to the classical subtype. Despite their prognostic and therapeutic value, the key drivers that establish...

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Detalles Bibliográficos
Autores principales: Adams, Christina R, Htwe, Htet Htwe, Marsh, Timothy, Wang, Aprilgate L, Montoya, Megan L, Subbaraj, Lakshmipriya, Tward, Aaron D, Bardeesy, Nabeel, Perera, Rushika M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538376/
https://www.ncbi.nlm.nih.gov/pubmed/31134896
http://dx.doi.org/10.7554/eLife.45313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538376/
https://www.ncbi.nlm.nih.gov/pubmed/31134896
http://dx.doi.org/10.7554/eLife.45313

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