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Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer
Pancreatic ductal adenocarcinoma (PDA) is a heterogeneous disease comprised of a basal-like subtype with mesenchymal gene signatures, undifferentiated histopathology and worse prognosis compared to the classical subtype. Despite their prognostic and therapeutic value, the key drivers that establish...
Autores principales: | Adams, Christina R, Htwe, Htet Htwe, Marsh, Timothy, Wang, Aprilgate L, Montoya, Megan L, Subbaraj, Lakshmipriya, Tward, Aaron D, Bardeesy, Nabeel, Perera, Rushika M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538376/ https://www.ncbi.nlm.nih.gov/pubmed/31134896 http://dx.doi.org/10.7554/eLife.45313 |
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