A generally conserved response to hypoxia in iPSC-derived cardiomyocytes from humans and chimpanzees

Despite anatomical similarities, there are differences in susceptibility to cardiovascular disease (CVD) between primates; humans are prone to myocardial ischemia, while chimpanzees are prone to myocardial fibrosis. Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) allow for direct int...

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Detalles Bibliográficos
Autores principales: Ward, Michelle C, Gilad, Yoav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538380/
https://www.ncbi.nlm.nih.gov/pubmed/30958265
http://dx.doi.org/10.7554/eLife.42374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538380/
https://www.ncbi.nlm.nih.gov/pubmed/30958265
http://dx.doi.org/10.7554/eLife.42374

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