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Immune regulation by protein ubiquitination: roles of the E3 ligases VHL and Itch
Protein ubiquitination is an important means of post-translational modification which plays an essential role in the regulation of various aspects of leukocyte development and function. The specificity of ubiquitin tagging to a protein substrate is determined by E3 ubiquitin ligases via defined E3-s...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538580/ https://www.ncbi.nlm.nih.gov/pubmed/30413999 http://dx.doi.org/10.1007/s13238-018-0586-8 |