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Encapsulation of a TRPM8 Agonist, WS12, in Lipid Nanocapsules Potentiates PC3 Prostate Cancer Cell Migration Inhibition through Channel Activation

In prostate carcinogenesis, expression and/or activation of the Transient Receptor Potential Melastatin 8 channel (TRPM8) was shown to block in vitro Prostate Cancer (PCa) cell migration. Because of their localization at the plasma membrane, ion channels, such as TRPM8 and other membrane receptors,...

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Detalles Bibliográficos
Autores principales: Grolez, G. P., Hammadi, M., Barras, A., Gordienko, D., Slomianny, C., Völkel, P., Angrand, P. O., Pinault, M., Guimaraes, C., Potier-Cartereau, M., Prevarskaya, N., Boukherroub, R., Gkika, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538610/
https://www.ncbi.nlm.nih.gov/pubmed/31138874
http://dx.doi.org/10.1038/s41598-019-44452-4