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Boosting BCG with proteins or rAd5 does not enhance protection against tuberculosis in rhesus macaques
Tuberculosis (TB) is the leading cause of death from infection worldwide. The only approved vaccine, BCG, has variable protective efficacy against pulmonary TB, the transmissible form of the disease. Therefore, improving this efficacy is an urgent priority. This study assessed whether heterologous p...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538611/ https://www.ncbi.nlm.nih.gov/pubmed/31149352 http://dx.doi.org/10.1038/s41541-019-0113-9 |