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The TLR4 agonist adjuvant SLA-SE promotes functional mucosal antibodies against a parenterally delivered ETEC vaccine

Many pathogens establish infection at mucosal surfaces such as the enteric pathogen Enterotoxigenic E. coli (ETEC). Thus, there is a pressing need for effective vaccination strategies that promote protective immunity at mucosal surfaces. Toll-like receptor (TLR) ligands have been extensively develop...

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Detalles Bibliográficos
Autores principales: Liang, Hong, Poncet, David, Seydoux, Emilie, Rintala, Nicholas D., Maciel, Milton, Ruiz, Sophie, Orr, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538625/
https://www.ncbi.nlm.nih.gov/pubmed/31149350
http://dx.doi.org/10.1038/s41541-019-0116-6