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The TLR4 agonist adjuvant SLA-SE promotes functional mucosal antibodies against a parenterally delivered ETEC vaccine
Many pathogens establish infection at mucosal surfaces such as the enteric pathogen Enterotoxigenic E. coli (ETEC). Thus, there is a pressing need for effective vaccination strategies that promote protective immunity at mucosal surfaces. Toll-like receptor (TLR) ligands have been extensively develop...
Autores principales: | Liang, Hong, Poncet, David, Seydoux, Emilie, Rintala, Nicholas D., Maciel, Milton, Ruiz, Sophie, Orr, Mark T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538625/ https://www.ncbi.nlm.nih.gov/pubmed/31149350 http://dx.doi.org/10.1038/s41541-019-0116-6 |
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