Targeting the transcription factor receptor LXR to treat clear cell renal cell carcinoma: agonist or inverse agonist?

Growing evidence indicates that clear cell renal cell carcinoma (ccRCC) is a metabolism-related disease. Changes in fatty acid (FA) and cholesterol metabolism play important roles in ccRCC development. As a nuclear transcription factor receptor, Liver X receptor (LXR) regulates a variety of key mole...

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Detalles Bibliográficos
Autores principales: Wu, Guangzhen, Wang, Qinglian, Xu, Yingkun, Li, Jianyi, Zhang, Hongge, Qi, Guanghui, Xia, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538631/
https://www.ncbi.nlm.nih.gov/pubmed/31138790
http://dx.doi.org/10.1038/s41419-019-1654-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538631/
https://www.ncbi.nlm.nih.gov/pubmed/31138790
http://dx.doi.org/10.1038/s41419-019-1654-6

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