Aptamer-based Targeted Delivery of a G-quadruplex Ligand in Cervical Cancer Cells

AS1411 is a G-rich DNA oligonucleotide that functions as an aptamer of the protein nucleolin, found at high levels on the surface of cancer cells but not on the surface of normal cells. Herein, we have studied AS1411 as a supramolecular carrier for the delivery of an acridine-based G-quadruplex liga...

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Detalles Bibliográficos
Autores principales: Carvalho, Josué, Paiva, Artur, Cabral Campello, Maria Paula, Paulo, António, Mergny, Jean-Louis, Salgado, Gilmar F., Queiroz, João A., Cruz, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538641/
https://www.ncbi.nlm.nih.gov/pubmed/31138870
http://dx.doi.org/10.1038/s41598-019-44388-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538641/
https://www.ncbi.nlm.nih.gov/pubmed/31138870
http://dx.doi.org/10.1038/s41598-019-44388-9

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