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Aptamer-based Targeted Delivery of a G-quadruplex Ligand in Cervical Cancer Cells
AS1411 is a G-rich DNA oligonucleotide that functions as an aptamer of the protein nucleolin, found at high levels on the surface of cancer cells but not on the surface of normal cells. Herein, we have studied AS1411 as a supramolecular carrier for the delivery of an acridine-based G-quadruplex liga...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538641/ https://www.ncbi.nlm.nih.gov/pubmed/31138870 http://dx.doi.org/10.1038/s41598-019-44388-9 |