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Interspecies conservation of organisation and function between nonhomologous regional centromeres

Despite the conserved essential function of centromeres, centromeric DNA itself is not conserved. The histone-H3 variant, CENP-A, is the epigenetic mark that specifies centromere identity. Paradoxically, CENP-A normally assembles on particular sequences at specific genomic locations. To gain insight...

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Detalles Bibliográficos
Autores principales: Tong, Pin, Pidoux, Alison L., Toda, Nicholas R. T., Ard, Ryan, Berger, Harald, Shukla, Manu, Torres-Garcia, Jesus, Müller, Carolin A., Nieduszynski, Conrad A., Allshire, Robin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538654/
https://www.ncbi.nlm.nih.gov/pubmed/31138803
http://dx.doi.org/10.1038/s41467-019-09824-4