Cargando…
Interspecies conservation of organisation and function between nonhomologous regional centromeres
Despite the conserved essential function of centromeres, centromeric DNA itself is not conserved. The histone-H3 variant, CENP-A, is the epigenetic mark that specifies centromere identity. Paradoxically, CENP-A normally assembles on particular sequences at specific genomic locations. To gain insight...
Autores principales: | Tong, Pin, Pidoux, Alison L., Toda, Nicholas R. T., Ard, Ryan, Berger, Harald, Shukla, Manu, Torres-Garcia, Jesus, Müller, Carolin A., Nieduszynski, Conrad A., Allshire, Robin C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538654/ https://www.ncbi.nlm.nih.gov/pubmed/31138803 http://dx.doi.org/10.1038/s41467-019-09824-4 |
Ejemplares similares
-
Centromere DNA Destabilizes H3 Nucleosomes to Promote CENP-A Deposition during the Cell Cycle
por: Shukla, Manu, et al.
Publicado: (2018) -
Sequence Features and Transcriptional Stalling within Centromere DNA Promote Establishment of CENP-A Chromatin
por: Catania, Sandra, et al.
Publicado: (2015) -
Sim4: a novel fission yeast kinetochore protein required for centromeric silencing and chromosome segregation
por: Pidoux, Alison L., et al.
Publicado: (2003) -
Establishment of centromere identity is dependent on nuclear spatial organization
por: Wu, Weifang, et al.
Publicado: (2022) -
Distinct roles for Sir2 and RNAi in centromeric heterochromatin nucleation, spreading and maintenance
por: Buscaino, Alessia, et al.
Publicado: (2013)