Cargando…

Translational downregulation of Twist1 expression by antiproliferative gene, B-cell translocation gene 2, in the triple negative breast cancer cells

Twist1, a key transcription factor regulating epithelial–mesenchymal transition and cancer metastasis, is highly expressed in invasive cancers in contrast to the loss of BTG2(/TIS21) expression. Based on our observation that forced expression of BTG2(/TIS21) downregulated Twist1 protein expression w...

Descripción completa

Detalles Bibliográficos
Autores principales: Devanand, Preethi, Sundaramoorthy, Santhoshkumar, Ryu, Min Sook, Jayabalan, Aravinth kumar, Ohn, Takbum, Lim, In Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538657/
https://www.ncbi.nlm.nih.gov/pubmed/31138781
http://dx.doi.org/10.1038/s41419-019-1640-z