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Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors
Recent history is punctuated by the emergence of highly pathogenic coronaviruses such as SARS- and MERS-CoV into human circulation. Upon infecting host cells, coronaviruses assemble a multi-subunit RNA-synthesis complex of viral non-structural proteins (nsp) responsible for the replication and trans...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538669/ https://www.ncbi.nlm.nih.gov/pubmed/31138817 http://dx.doi.org/10.1038/s41467-019-10280-3 |