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Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors

Recent history is punctuated by the emergence of highly pathogenic coronaviruses such as SARS- and MERS-CoV into human circulation. Upon infecting host cells, coronaviruses assemble a multi-subunit RNA-synthesis complex of viral non-structural proteins (nsp) responsible for the replication and trans...

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Detalles Bibliográficos
Autores principales:	Kirchdoerfer, Robert N., Ward, Andrew B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538669/ https://www.ncbi.nlm.nih.gov/pubmed/31138817 http://dx.doi.org/10.1038/s41467-019-10280-3

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