The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

The collapse of stalled replication forks is a major driver of genomic instability. Several committed mechanisms exist to resolve replication stress. These pathways are particularly pertinent at telomeres. Cancer cells that use Alternative Lengthening of Telomeres (ALT) display heightened levels of...

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Detalles Bibliográficos
Autores principales: Lu, Robert, O’Rourke, Julienne J., Sobinoff, Alexander P., Allen, Joshua A. M., Nelson, Christopher B., Tomlinson, Christopher G., Lee, Michael, Reddel, Roger R., Deans, Andrew J., Pickett, Hilda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538672/
https://www.ncbi.nlm.nih.gov/pubmed/31138797
http://dx.doi.org/10.1038/s41467-019-10180-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538672/
https://www.ncbi.nlm.nih.gov/pubmed/31138797
http://dx.doi.org/10.1038/s41467-019-10180-6

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