A juxtacrine/paracrine loop between C-Kit and stem cell factor promotes cancer stem cell survival in epithelial ovarian cancer

Receptors tyrosine kinase (RTK) enable normal and tumor cells to perceive and adapt to stimuli present in the microenvironment. These stimuli, also known as growth factors, are important molecular cues actively supporting cancer stem cell (CSC) self-renewal and viability. Since in epithelial ovarian...

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Detalles Bibliográficos
Autores principales: Mazzoldi, Elena Laura, Pavan, Simona, Pilotto, Giorgia, Leone, Kevin, Pagotto, Anna, Frezzini, Simona, Nicoletto, Maria Ornella, Amadori, Alberto, Pastò, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538673/
https://www.ncbi.nlm.nih.gov/pubmed/31138788
http://dx.doi.org/10.1038/s41419-019-1656-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538673/
https://www.ncbi.nlm.nih.gov/pubmed/31138788
http://dx.doi.org/10.1038/s41419-019-1656-4

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