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Inhibition of eIF2α dephosphorylation accelerates pterostilbene-induced cell death in human hepatocellular carcinoma cells in an ER stress and autophagy-dependent manner

Hepatocellular carcinoma (HCC) is the one of the most common cancers worldwide. Because the side effects of current treatments are severe, new effective therapeutic strategies are urgently required. Pterostilbene (PT), a natural analogue of resveratrol, has diverse pharmacologic activities, includin...

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Detalles Bibliográficos
Autores principales: Yu, Chen-Lin, Yang, Shun-Fa, Hung, Tung-Wei, Lin, Chia-Liang, Hsieh, Yi-Hsien, Chiou, Hui-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538697/
https://www.ncbi.nlm.nih.gov/pubmed/31138785
http://dx.doi.org/10.1038/s41419-019-1639-5