The appropriate frequency and function of decidual Tim-3(+)CTLA-4(+)CD8(+) T cells are important in maintaining normal pregnancy

Maternal decidual CD8(+) T (dCD8(+) T) cells must integrate the antithetical demands of maternal–fetal tolerance and anti-viral immunity to establish a successful pregnancy. T-cell immunoglobulin mucin-3 (Tim-3) and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) are two important co-inhibitory...

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Detalles Bibliográficos
Autores principales: Wang, Songcun, Sun, Fengrun, Li, Mengdie, Qian, Jinfeng, Chen, Chunqin, Wang, Mingyan, Zang, Xingxing, Li, Dajin, Yu, Min, Du, Meirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538701/
https://www.ncbi.nlm.nih.gov/pubmed/31138782
http://dx.doi.org/10.1038/s41419-019-1642-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538701/
https://www.ncbi.nlm.nih.gov/pubmed/31138782
http://dx.doi.org/10.1038/s41419-019-1642-x

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