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Evaluation of the inverse electron demand Diels-Alder reaction in rats using a scandium-44-labelled tetrazine for pretargeted PET imaging

BACKGROUND: Pretargeted imaging allows the use of short-lived radionuclides when imaging the accumulation of slow clearing targeting agents such as antibodies. The biotin-(strept)avidin and the bispecific antibody-hapten interactions have been applied in clinical pretargeting studies; unfortunately,...

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Detalles Bibliográficos
Autores principales: Edem, Patricia E., Sinnes, Jean-Philippe, Pektor, Stefanie, Bausbacher, Nicole, Rossin, Raffaella, Yazdani, Abdolreza, Miederer, Matthias, Kjær, Andreas, Valliant, John F., Robillard, Marc S., Rösch, Frank, Herth, Matthias M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538705/
https://www.ncbi.nlm.nih.gov/pubmed/31140047
http://dx.doi.org/10.1186/s13550-019-0520-y