An electrochemiluminescence based assay for quantitative detection of endogenous and exogenously applied MeCP2 protein variants

Methyl-CpG-binding protein 2 (MeCP2) is a multifunctional chromosomal protein that plays a key role in the central nervous system. Its levels need to be tightly regulated, as both deficiency and excess of the protein can lead to severe neuronal dysfunction. Loss-of-function mutations affecting MeCP2...

Descripción completa

Detalles Bibliográficos
Autores principales: Steinkellner, Hannes, Schönegger, Anna, Etzler, Julia, Kempaiah, Prakasha, Huber, Anna, Hahn, Kathrin, Rose, Katrin, Duerr, Mark, Christodoulou, John, Beribisky, Alexander V., Neuhaus, Winfried, Laccone, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538716/
https://www.ncbi.nlm.nih.gov/pubmed/31138832
http://dx.doi.org/10.1038/s41598-019-44372-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538716/
https://www.ncbi.nlm.nih.gov/pubmed/31138832
http://dx.doi.org/10.1038/s41598-019-44372-3

Ejemplares similares