Cannabidiol Affects the Bezold-Jarisch Reflex via TRPV1 and 5-HT(3) Receptors and Has Peripheral Sympathomimetic Effects in Spontaneously Hypertensive and Normotensive Rats

Cannabidiol (CBD) is a nonpsychotropic constituent of Cannabis sativa L. It is suggested to be useful in hypertension. Under in vitro conditions, it activates vanilloid TRPV1 and inhibits serotonin 5-HT(3) receptors, i.e., receptors involved in the Bezold-Jarisch reflex stimulation. The aim of our s...

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Detalles Bibliográficos
Autores principales: Kossakowski, Rafał, Schlicker, Eberhard, Toczek, Marek, Weresa, Jolanta, Malinowska, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538767/
https://www.ncbi.nlm.nih.gov/pubmed/31178718
http://dx.doi.org/10.3389/fphar.2019.00500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538767/
https://www.ncbi.nlm.nih.gov/pubmed/31178718
http://dx.doi.org/10.3389/fphar.2019.00500

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