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Cannabidiol Affects the Bezold-Jarisch Reflex via TRPV1 and 5-HT(3) Receptors and Has Peripheral Sympathomimetic Effects in Spontaneously Hypertensive and Normotensive Rats
Cannabidiol (CBD) is a nonpsychotropic constituent of Cannabis sativa L. It is suggested to be useful in hypertension. Under in vitro conditions, it activates vanilloid TRPV1 and inhibits serotonin 5-HT(3) receptors, i.e., receptors involved in the Bezold-Jarisch reflex stimulation. The aim of our s...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538767/ https://www.ncbi.nlm.nih.gov/pubmed/31178718 http://dx.doi.org/10.3389/fphar.2019.00500 |