Binding Heterogeneity of Plasmodium falciparum to Engineered 3D Brain Microvessels Is Mediated by EPCR and ICAM-1

Cerebral malaria is a severe neurological complication associated with sequestration of Plasmodium falciparum-infected erythrocytes (IE) in the brain microvasculature, but the specific binding interactions remain under debate. Here, we have generated an engineered three-dimensional (3D) human brain...

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Detalles Bibliográficos
Autores principales: Bernabeu, Maria, Gunnarsson, Celina, Vishnyakova, Maria, Howard, Caitlin C., Nagao, Ryan J., Avril, Marion, Taylor, Terrie E., Seydel, Karl B., Zheng, Ying, Smith, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538777/
https://www.ncbi.nlm.nih.gov/pubmed/31138740
http://dx.doi.org/10.1128/mBio.00420-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538777/
https://www.ncbi.nlm.nih.gov/pubmed/31138740
http://dx.doi.org/10.1128/mBio.00420-19

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