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Modification of the Gastric Mucosal Microbiota by a Strain-Specific Helicobacter pylori Oncoprotein and Carcinogenic Histologic Phenotype

Helicobacter pylori is the strongest risk factor for gastric adenocarcinoma; however, most infected individuals never develop this malignancy. Strain-specific microbial factors, such as the oncoprotein CagA, as well as environmental conditions, such as iron deficiency, augment cancer risk. Important...

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Detalles Bibliográficos
Autores principales: Noto, Jennifer M., Zackular, Joseph P., Varga, Matthew G., Delgado, Alberto, Romero-Gallo, Judith, Scholz, Matthew B., Piazuelo, M. Blanca, Skaar, Eric P., Peek, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538789/
https://www.ncbi.nlm.nih.gov/pubmed/31138752
http://dx.doi.org/10.1128/mBio.00955-19