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Stachydrine Ameliorates Cardiac Fibrosis Through Inhibition of Angiotensin II/Transformation Growth Factor β1 Fibrogenic Axis

Cardiovascular diseases, the leading cause of death worldwide, are tightly associated with the pathological myocardial fibrosis. Stachydrine (Sta), a major active compound in Chinese motherwort Leonurus heterophyllus, was reported to effectively attenuate cardiac fibrosis, but the cellular and molec...

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Detalles Bibliográficos
Autores principales: Liu, Xiao, Shan, Xiaoli, Chen, Huihua, Li, Zan, Zhao, Pei, Zhang, Chen, Guo, Wei, Xu, Ming, Lu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538804/
https://www.ncbi.nlm.nih.gov/pubmed/31178725
http://dx.doi.org/10.3389/fphar.2019.00538