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Grape seed procyanidin B2 promotes the autophagy and apoptosis in colorectal cancer cells via regulating PI3K/Akt signaling pathway

Aim: Colorectal cancer (CRC) is a major malignancy in China, which is the critical risk of people health. Many natural herbs extracts have been found to exhibit good therapeutic effect on CRC. Our previous study found that grape seed procyanidins B2 (PB2) would induce CRC cell death. However, the mo...

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Detalles Bibliográficos
Autores principales: Zhang, Ruijuan, Yu, Qianyun, Lu, Wenqiang, Shen, Jun, Zhou, Dongqing, Wang, Yingjue, Gao, Shurong, Wang, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538883/
https://www.ncbi.nlm.nih.gov/pubmed/31213831
http://dx.doi.org/10.2147/OTT.S195615