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Advanced Technology for Gene Delivery with Homing Peptides to Spinal Cord through Systemic Circulation in Mice

Homing peptides to the spinal cord were identified and isolated using phage display technology. In vivo biopanning was performed by intravenous systemic injection of a phage library to screen specific peptides targeting the spinal cord of mice. Analyses of the sequences of targeted phages yielded tw...

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Detalles Bibliográficos
Autores principales: Terashima, Tomoya, Ogawa, Nobuhiro, Sato, Toshiyuki, Katagi, Miwako, Nakae, Yuki, Okano, Junko, Maegawa, Hiroshi, Kojima, Hideto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538929/
https://www.ncbi.nlm.nih.gov/pubmed/31193742
http://dx.doi.org/10.1016/j.omtm.2019.04.008