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Necroptosis of Intestinal Epithelial Cells Induces Type 3 Innate Lymphoid Cell-Dependent Lethal Ileitis

A short form of cellular FLICE-inhibitory protein encoded by CFLARs promotes necroptosis. Although necroptosis is involved in various pathological conditions, the detailed mechanisms are not fully understood. Here we generated transgenic mice wherein CFLARs was integrated onto the X chromosome. All...

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Detalles Bibliográficos
Autores principales: Shindo, Ryodai, Ohmuraya, Masaki, Komazawa-Sakon, Sachiko, Miyake, Sanae, Deguchi, Yutaka, Yamazaki, Soh, Nishina, Takashi, Yoshimoto, Takayuki, Kakuta, Soichiro, Koike, Masato, Uchiyama, Yasuo, Konishi, Hiroyuki, Kiyama, Hiroshi, Mikami, Tetuo, Moriwaki, Kenta, Araki, Kimi, Nakano, Hiroyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538961/
https://www.ncbi.nlm.nih.gov/pubmed/31132747
http://dx.doi.org/10.1016/j.isci.2019.05.011