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Necroptosis of Intestinal Epithelial Cells Induces Type 3 Innate Lymphoid Cell-Dependent Lethal Ileitis
A short form of cellular FLICE-inhibitory protein encoded by CFLARs promotes necroptosis. Although necroptosis is involved in various pathological conditions, the detailed mechanisms are not fully understood. Here we generated transgenic mice wherein CFLARs was integrated onto the X chromosome. All...
Autores principales: | Shindo, Ryodai, Ohmuraya, Masaki, Komazawa-Sakon, Sachiko, Miyake, Sanae, Deguchi, Yutaka, Yamazaki, Soh, Nishina, Takashi, Yoshimoto, Takayuki, Kakuta, Soichiro, Koike, Masato, Uchiyama, Yasuo, Konishi, Hiroyuki, Kiyama, Hiroshi, Mikami, Tetuo, Moriwaki, Kenta, Araki, Kimi, Nakano, Hiroyasu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538961/ https://www.ncbi.nlm.nih.gov/pubmed/31132747 http://dx.doi.org/10.1016/j.isci.2019.05.011 |
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