Sodium-Hydrogen Exchanger Isoform-1 Inhibition: A Promising Pharmacological Intervention for Resuscitation from Cardiac Arrest

Out-of-hospital sudden cardiac arrest is a major public health problem with an overall survival of less than 5%. Upon cardiac arrest, cessation of coronary blood flow rapidly leads to intense myocardial ischemia and activation of the sarcolemmal Na(+)-H(+) exchanger isoform-1 (NHE-1). NHE-1 activati...

Descripción completa

Detalles Bibliográficos
Autores principales: Gazmuri, Raúl J., Radhakrishnan, Jeejabai, Ayoub, Iyad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538998/
https://www.ncbi.nlm.nih.gov/pubmed/31067690
http://dx.doi.org/10.3390/molecules24091765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538998/
https://www.ncbi.nlm.nih.gov/pubmed/31067690
http://dx.doi.org/10.3390/molecules24091765

Ejemplares similares